Bacterial and yeast skin infections are among the most common dermatological conditions seen in dogs and cats. Pyoderma (bacterial), Malassezia overgrowth (yeast), and mixed infections frequently present with red, irritated skin, an unpleasant odour, excessive scratching, and hair loss — and they can recur repeatedly if the skin's microbiome is not actively supported between veterinary treatments. Topical antiseptic care between episodes is a key component of long-term skin health management.
Ceva DOUXO S3 PYO is a veterinary dermatology line formulated specifically for dogs and cats with microbial skin conditions — bacterial pyoderma, Malassezia dermatitis, or mixed infections. The PYO line contains two active antiseptic agents — chlorhexidine (3%) and climbazole — combined with Ceva's proprietary Ophytrium technology to simultaneously fight infection and restore skin barrier integrity. Available in three formats: mousse (150 ml), shampoo (200 ml and 500 ml), and antiseptic pads (30-pack).
Key Active Ingredients
Chlorhexidine 3%: A broad-spectrum antiseptic with proven bactericidal and fungicidal activity. Effective against Staphylococcus pseudintermedius (the primary cause of canine pyoderma) and Malassezia pachydermatis (the primary yeast involved in otitis and skin infections).
Climbazole: An antifungal specifically active against Malassezia species, providing targeted yeast control in combination with chlorhexidine's broader antimicrobial action.
Ophytrium (Ophiopogon japonicus extract): Ceva's patented ingredient that supports the skin microbiome, strengthens the skin barrier, and reduces inflammation — addressing the underlying skin vulnerability that allows infections to recur.
Format Guide
| Format |
Best For |
| Shampoo 200 ml |
Whole-body antiseptic bathing, smaller dogs/cats |
| Shampoo 500 ml |
Whole-body bathing, larger dogs or frequent use |
| Mousse 150 ml |
Spot treatment, areas difficult to rinse, between baths |
| Pads 30/pack |
Localized areas, skin folds, paws, post-bathing maintenance |
Supplement Advisor's Note
DOUXO S3 PYO is most effective as part of a structured antiseptic protocol — typically twice-weekly bathing or mousse application during active infection, tapering to once weekly for maintenance. The Ophytrium component is what distinguishes DOUXO from older chlorhexidine-only products: it addresses the skin barrier disruption that makes these dogs and cats vulnerable to recurrent infection. For dogs with recurrent pyoderma, combining regular DOUXO PYO use with dietary omega-3 supplementation often produces better long-term outcomes than topical treatment alone.
Frequently Asked Questions
How often should I use DOUXO S3 PYO?
During active infection: 2–3 times per week. For maintenance to prevent recurrence: once weekly. Always follow your veterinarian's specific recommendation based on your pet's condition.
Can I use DOUXO S3 PYO without a veterinary diagnosis?
DOUXO S3 PYO is available without a prescription and can be used for mild skin irritation. However, for persistent or worsening skin conditions, a veterinary diagnosis is recommended to rule out underlying causes and ensure appropriate treatment.
Is DOUXO S3 PYO safe for cats?
Yes — it is formulated for both dogs and cats. Chlorhexidine at 3% is safe for topical feline use when applied correctly and allowed to dry fully before the cat grooms. Avoid application near eyes and mouth.
What is the difference between DOUXO S3 PYO, SEB, and Calm?
PYO targets bacterial and yeast infections (antiseptic). SEB addresses seborrhoeic conditions — flaking, greasiness, and sebaceous gland dysfunction. Calm is designed for sensitive and atopic skin with a focus on itch and inflammation reduction. Each targets a different dermatological profile.
